Frailty Syndrome: Basic and Clinical Aspects Published by CRC Press

Frailty Syndrome: Basic and Clinical Aspects, a new academic volume published by CRC Press, brings together contemporary perspectives on the biology, assessment, prevention, and clinical management of frailty.

Edited by María Carmen Gómez-Cabrera, José Viña, and Leocadio Rodríguez-Mañas, the volume brings together researchers working across geriatric medicine, physiology, nutrition, physical activity, metabolism, and the biology of aging.

The book approaches frailty as a multidimensional geriatric syndrome, moving from conceptual and biological foundations to practical issues in prevention and clinical management. Particular attention is given to the relationship between frailty and intrinsic capacity, biomarkers, physical activity, nutrition, metabolic disease, resilience, cognition, the microbiome, and experimental models of aging.

Table of Contents

1. Unveiling Vulnerability: Frailty in the Lens of Intrinsic CapacityLuis Miguel F. Gutiérrez Robledo, Brenda Amelia Casasola Espinosa
2. Clinical Management of Frailty: Advances and ChallengesIsabel Rodríguez Sánchez, Alejandro Alvarez-Bustos, Mariam El Assar de la Fuente, Leocadio Rodriguez-Mañas
3. Biomarkers of FrailtyMariam El Assar de la Fuente, Isabel Rodríguez-Sánchez, Alejandro Álvarez-Bustos, Leocadio Rodríguez-Mañas
4. Physical Activity and Exercise in the Prevention and Treatment of FrailtyHélio José Coelho-Júnior, Riccardo Calvani, Emanuele Marzetti
5. Crosstalk between Fat, Bone Mineral Density, Muscle, and FrailtyAna María Ayala Copete, Daniel Rivas, Gustavo Duque
6. Nutrition and Frailty: Epidemiological and Clinical FactsStefano Cacciatore, Francesco Landi
7. Physical Function-Based Programs in FrailtyEleftheria Antoniou
8. Diabetes and Frailty: Interactions and Clinical ImplicationsAlan J. Sinclair, A. H. Abdelhafiz
9. Complexity and Disentanglement of Frailty: The Biopsychosocial Model of Frailty and ResilienceM. Cristina Polidori
10. The Impact of Polyphenol Intake on Cognitive Decline: Insights from Plasma and Urine Biomarker AnalysisAlba Tor-Roca, Cristina Andrés-Lacueva, Antonio Cherubini, Mireia Urpí-Sardà
11. The Role of the Microbiota in Aging and FrailtyMónica De la Fuente, Eduardo Ortega
12. Frailty in Experimental Animals: Models and ScoresLaDora V. Thompson

Together, the chapters provide a broad overview of a rapidly evolving field and illustrate how frailty research increasingly connects biological mechanisms with clinical and preventive approaches to healthy aging.